INSTITUTII

	Institute on Normal and Pathological Physiology
Name of institution	Institute on Normal and Pathological Physiology "D. Danielopolu"
Address	11, Ion Mihalache blvd., 78173 Bucharest, Romania
Phone/Facsimile	40-1-312 89 38 / 40-1-312 59 37
Key personnel	Director: Dr. M. Uluitu Deputy director: Dr. M. Bordea
Structure and Activities	Start of activities: 1961 Main activities Experimental and clinical physiology Pathophysiology of cardiovascular, kidney, digestive and hepatic functions
Main Specializations	Chemical mediation at the level of encephalic centers; Cerebral excitability - role of cations, processes of behaviourial integration; Lithium-organism interrelations, reflex influence, immune processes; Cardio-haemodynamic regulation.
Space Specializations	Hydroelectrolytic balance during gravitational variations in relation with cerebral excitability in experimental conditions; Complex haemodynamic metabolic regulation for pilots of supersonic aircraft; Immune response during gravitational variations.
Personnel	Total personnel: 123

SPACE RESEARCH TOPICS AND PROJECTS DURING 1998-1999

• Studies on the molecular and cellular mechanisms manifested in the hydroelectrolitic homeostasy maintaining and immunologic processes evolution in virtual space conditions (microgravity, radiations)
• Studies and modeling of the action mechanism of some chemicals of pharmacologic and medical interest by means of relations structure-biologic activity in space conditions